Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374453 | 0.88 | HSD17B10 (0.64) | HSD17B10KCNH2HRH3MEN1KMT2A | |
| SCHEMBL8241804 | 0.87 | KCNH2 (0.67) | KCNH2HRH3MEN1KMT2AAPOBEC3A | |
| SCHEMBL4577022 | 0.84 | KCNH2 (0.64) | KCNH2HRH3MEN1KMT2AAPOBEC3A | |
| SCHEMBL2375481 | 0.83 | OPRK1 (0.71) | MEN1KMT2APOLBOPRK1 | |
| SCHEMBL2375476 | 0.83 | OPRK1 (0.71) | MEN1KMT2APOLBOPRK1 | |
| SCHEMBL23717918 | 0.83 | KCNH2 (0.62) | KCNH2HRH3MEN1KMT2AAPOBEC3A | |
| SCHEMBL16252295 | 0.83 | POLB (0.63) | KCNH2HRH3MEN1KMT2AAPOBEC3A | |
| SCHEMBL16254373 | 0.83 | POLB (0.66) | KCNH2HRH3MEN1KMT2AAPOBEC3A | |
| SCHEMBL9906598 | 0.82 | HSD17B10 (0.64) | HSD17B10MEN1KMT2AAPOBEC3AAPOBEC3G | |
| SCHEMBL5374449 | 0.82 | HSD17B10 (0.64) | HSD17B10KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997009310-A1 | 1-PHENYL-3-4-[BENZYLPIPERIDINYL-1]-PROPANOL-1 DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATION THEREOF | SYNTHELABO (FR) | 1997-03-13 | — | — | WO | disclosed |