Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 5/20 | 0.73 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.72 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8900133 | 0.99 | MERTK (0.72) | MERTKNPY5RSLC2A1MEN1KMT2A | |
| SCHEMBL8892609 | 0.91 | KDM4E (0.67) | MERTKNPY5RSLC2A1MEN1KMT2A | |
| SCHEMBL8890638 | 0.90 | NPY5R (0.67) | MERTKNPY5RKMT2AMAPTALDH1A1 | |
| SCHEMBL8889582 | 0.87 | NPY5R (0.76) | MERTKNPY5RSLC2A1MEN1KMT2A | |
| SCHEMBL2590796 | 0.86 | NPY5R (0.97) | MERTKNPY5RSLC2A1MEN1KMT2A | |
| SCHEMBL16404310 | 0.85 | NPY5R (0.73) | MERTKNPY5RSLC2A1MEN1KMT2A | |
| SCHEMBL8909187 | 0.85 | NPY5R (1.00) | MERTKNPY5RSLC2A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8897702 | 0.85 | NPY5R (0.94) | MERTKNPY5RSLC2A1MEN1KMT2A | |
| SCHEMBL8892796 | 0.84 | NPY5R (0.76) | MERTKNPY5RSLC2A1MEN1KMT2A | |
| SCHEMBL8889361 | 0.84 | KDM4E (0.70) | MERTKNPY5RSLC2A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |