Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.67 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MERTK | Q12866 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PGK1 | P00558 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889728 | 0.92 | NPY5R (0.70) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| SCHEMBL8890526 | 0.91 | TAAR1 (0.65) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8908244 | 0.91 | NPY5R (0.68) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| SCHEMBL8891140 | 0.90 | NPY5R (0.60) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| SCHEMBL8891485 | 0.90 | MERTK (0.73) | NPY5RTAAR1HTTSMN1; SMN2MERTK | |
| Hydrochloric Acid SCHEMBL8908695 | 0.89 | NPY5R (0.59) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8900133 | 0.89 | MERTK (0.72) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| SCHEMBL8892609 | 0.87 | KDM4E (0.67) | NPY5RTAAR1HTTSMN1; SMN2MERTK | |
| SCHEMBL8890752 | 0.83 | MERTK (0.69) | NPY5RTAAR1HTTPOLBSMN1; SMN2 | |
| SCHEMBL27223492 | 0.82 | NPY5R (0.62) | NPY5RTAAR1HTTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |