Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 6/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412059 | 0.91 | ACE (0.66) | ACEF2PRSS1CMA1CTRC | |
| SCHEMBL7087290 | 0.91 | ACE (0.66) | ACEF2PRSS1CMA1CTRC | |
| SCHEMBL6412055 | 0.91 | ACE (0.66) | ACEF2PRSS1CMA1CTRC | |
| SCHEMBL16667799 | 0.90 | KLK5 (0.58) | ACEF2PRSS1CMA1CTSS | |
| SCHEMBL864626 | 0.85 | XIAP (0.46) | ACEF2PRSS1OPRM1CMA1 | |
| SCHEMBL864625 | 0.85 | XIAP (0.46) | ACEF2PRSS1OPRM1CMA1 | |
| SCHEMBL864624 | 0.85 | XIAP (0.46) | ACEF2PRSS1OPRM1CMA1 | |
| SCHEMBL10604343 | 0.85 | ACE (0.52) | ACEF2PRSS1CMA1CTSS | |
| SCHEMBL10604335 | 0.85 | ACE (0.52) | ACEF2PRSS1CMA1CTSS | |
| SCHEMBL18257107 | 0.83 | ACE (0.57) | ACEF2PRSS1CMA1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599791-A | BACTERICIDE ACTIVE AGAINST GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA | GRUPPO LEPETIT SPA (IT) | 1997-02-04 | — | — | US | disclosed |
| EP-0565567-B1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | LEPETIT SPA (IT) | 1995-01-18 | — | — | EP | disclosed |
| EP-0494078-A1 | Amides of antibiotic ge 2270 factors | GRUPPO LEPETIT S.p.A. (IT) | 1992-07-08 | — | — | EP | disclosed |