Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604343 | 1.00 | ACE (0.52) | ACECTSSCTSKF2PRSS1 | |
| SCHEMBL10605848 | 0.91 | ACE (0.62) | ACECTSSCTSKF2PRSS1 | |
| SCHEMBL10605836 | 0.91 | ACE (0.62) | ACECTSSCTSKF2PRSS1 | |
| SCHEMBL8891583 | 0.85 | ACE (0.55) | ACECTSSCTSKF2PRSS1 | |
| SCHEMBL16667799 | 0.85 | KLK5 (0.58) | ACECTSSCTSKF2PRSS1 | |
| SCHEMBL10604631 | 0.82 | ACE (0.42) | ACECTSSCTSKF2PRSS1 | |
| SCHEMBL10604644 | 0.82 | ACE (0.42) | ACECTSSCTSKF2PRSS1 | |
| SCHEMBL15110005 | 0.81 | CTSS (0.58) | CTSSCTSKKMT2APABPC1MAPK1 | |
| SCHEMBL18257089 | 0.80 | HDAC1 (0.51) | ACECTSSCTSKF2PRSS1 | |
| SCHEMBL18257086 | 0.80 | HDAC1 (0.51) | ACECTSSCTSKF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154353-B1 | AN ANTI-AMNESTIC AGENT | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-11-15 | — | — | EP | disclosed |
| US-4687778-A | Anti-amnestic agent | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1987-08-18 | — | — | US | disclosed |
| EP-0154353-A2 | An anti-amnestic agent | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1985-09-11 | — | — | EP | disclosed |