SCHEMBL8891701

SCHEMBL8891701

CCC1(C(=O)O)C2CC(Cc3ccccc3C)C(C#N)(C(=O)CN)C21

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.30
FAP Q12884 2/20 0.30
DPP8 Q6V1X1 2/20 0.30
DPP9 Q86TI2 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8901310 0.89 GAA (0.33)
SCHEMBL8764447 0.89
SCHEMBL8891969 0.89
SCHEMBL8892210 0.87
SCHEMBL8900909 0.86 RECQL (0.31)
SCHEMBL8901107 0.84 CTSC (0.32) DPP4FAPDPP8DPP9
SCHEMBL8891411 0.81 MEN1 (0.32) DPP4
SCHEMBL8894509 0.81 TSHR (0.30)
SCHEMBL8892402 0.81 GRM2 (0.33)
SCHEMBL8892238 0.80 CCR8 (0.36) DPP4FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997017950-A1 SHOULDER PROSTHESIS ELI LILLY AND COMPANY (US) 1997-05-22 WO disclosed