Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892810 | 1.00 | GRM2 (0.33) | GRM2GRM3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8902155 | 0.93 | GRM2 (0.34) | GRM2GRM3 | |
| SCHEMBL8892171 | 0.86 | GRM2 (0.37) | GRM2GRM3SLC6A2SLC6A4 | |
| SCHEMBL8892694 | 0.86 | — | — | |
| SCHEMBL8894509 | 0.86 | TSHR (0.30) | GRM2GRM3 | |
| SCHEMBL8764713 | 0.85 | ALDH1A1 (0.33) | GRM2GRM3 | |
| SCHEMBL8891106 | 0.85 | MAOA (0.30) | — | |
| SCHEMBL8892210 | 0.82 | — | — | |
| SCHEMBL8891969 | 0.81 | — | — | |
| SCHEMBL8764447 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997017950-A1 | SHOULDER PROSTHESIS | ELI LILLY AND COMPANY (US) | 1997-05-22 | — | — | WO | disclosed |