Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.62 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.62 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897245 | 0.87 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2LTB4RLTB4R2 | |
| SCHEMBL8897252 | 0.87 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2LTB4RLTB4R2 | |
| SCHEMBL8889148 | 0.83 | CYSLTR1 (0.75) | CYSLTR1CYSLTR2PTGER4LTB4RLTB4R2 | |
| SCHEMBL8889821 | 0.83 | CYSLTR1 (0.75) | CYSLTR1CYSLTR2PTGER4LTB4RLTB4R2 | |
| SCHEMBL8889138 | 0.83 | CYSLTR1 (0.75) | CYSLTR1CYSLTR2PTGER4LTB4RLTB4R2 | |
| SCHEMBL8898787 | 0.82 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2LTB4RLTB4R2 | |
| SCHEMBL8898782 | 0.82 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2LTB4RLTB4R2 | |
| SCHEMBL8888630 | 0.80 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2PTGER4LTB4RLTB4R2 | |
| SCHEMBL8888621 | 0.80 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2PTGER4LTB4RLTB4R2 | |
| SCHEMBL8892969 | 0.79 | CYSLTR2 (0.45) | CYSLTR1CYSLTR2LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641789-A | INHIBITORS OF LEUKOTRIENES AND/OR BLOCKERS OF LEUKOTRIENE RECEPTORS; USEFUL IN PREVENTION OR TREATMENT OF ASTHMA, ARTHRITIS, PSORIASIS, ULCERS, MYOCARDIAL INFARCTION | PFIZER INC. (US) | 1997-06-24 | — | — | US | disclosed |