Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.58 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12120077 | 1.00 | NAAA (0.58) | NAAADGKADNM1THRATHRB | |
| SCHEMBL12120073 | 1.00 | NAAA (0.58) | NAAADGKADNM1THRATHRB | |
| SCHEMBL12120081 | 1.00 | NAAA (0.58) | NAAADGKADNM1THRATHRB | |
| SCHEMBL12120074 | 1.00 | NAAA (0.58) | NAAADGKADNM1THRATHRB | |
| SCHEMBL12120078 | 0.98 | NAAA (0.55) | NAAADGKADNM1THRATHRB | |
| SCHEMBL12792293 | 0.96 | NAAA (0.58) | NAAADGKADNM1THRATHRB | |
| SCHEMBL27329949 | 0.96 | NAAA (0.58) | NAAADGKADNM1THRATHRB | |
| SCHEMBL12792363 | 0.96 | NAAA (0.58) | NAAADGKADNM1THRATHRB | |
| SCHEMBL889262 | 0.96 | NAAA (0.58) | NAAADGKADNM1THRATHRB | |
| SCHEMBL27329950 | 0.96 | NAAA (0.58) | NAAADGKADNM1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009222-A1 | MODULATION OF THE IMMUNE RESPONSE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009222-A1 | MODULATION OF THE IMMUNE RESPONSE | FCGRT, MYD88, C3AR1 | NAAA 789/4885DGKA 1291/4885DNM1 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.