Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.35 |
| ▸ | TUBB | P07437 | 3/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589367 | 0.86 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1LMNAMEN1 | |
| SCHEMBL8671632 | 0.86 | PTGS1 (0.40) | PTGS1PTGS2SLC2A1LMNAMEN1 | |
| SCHEMBL8649724 | 0.82 | SLC2A1 (0.37) | PTGS1PTGS2SLC2A1LMNAMEN1 | |
| SCHEMBL8643263 | 0.82 | SLC2A1 (0.35) | PTGS1PTGS2SLC2A1LMNAMEN1 | |
| SCHEMBL8645272 | 0.82 | LMNA (0.36) | PTGS1PTGS2SLC2A1LMNAMEN1 | |
| SCHEMBL8642031 | 0.81 | SLC2A1 (0.35) | PTGS1PTGS2SLC2A1LMNAMEN1 | |
| SCHEMBL8646867 | 0.81 | PTPN5 (0.38) | PTGS1PTGS2SLC2A1LMNAMEN1 | |
| SCHEMBL8661485 | 0.81 | LMNA (0.35) | PTGS1PTGS2SLC2A1LMNAMEN1 | |
| SCHEMBL8668568 | 0.81 | PTGS1 (0.42) | PTGS1PTGS2SLC2A1LMNAMEN1 | |
| SCHEMBL8643253 | 0.80 | SLC2A1 (0.35) | PTGS1PTGS2SLC2A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | disclosed |