Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 14/20 | 0.59 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | AQP1 | P29972 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8898590 | 0.99 | NPY5R (0.58) | NPY5RAPPBCHEACHEAQP1 | |
| SCHEMBL8900891 | 0.84 | NPY5R (0.53) | NPY5RAPPBCHEACHEADRA2A | |
| SCHEMBL8900899 | 0.84 | NPY5R (0.61) | NPY5RAPPBCHEACHEAQP1 | |
| Hydrochloric Acid SCHEMBL8901970 | 0.83 | NPY5R (0.53) | NPY5RAPPBCHEACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL8901980 | 0.83 | NPY5R (0.60) | NPY5RAPPBCHEACHEAQP1 | |
| SCHEMBL8892223 | 0.81 | NPY5R (0.59) | NPY5RAPPBCHEACHEAQP1 | |
| Hydrochloric Acid SCHEMBL8898597 | 0.81 | NPY5R (0.58) | NPY5RAPPBCHEACHEAQP1 | |
| SCHEMBL11735631 | 0.78 | NPY5R (0.64) | NPY5RAPPBCHEACHENPC1 | |
| Hydrochloric Acid SCHEMBL6929267 | 0.76 | KDM4E (0.61) | ALDH1A1MAPTHPGDMCHR1TP53 | |
| SCHEMBL8890141 | 0.76 | KDM4E (0.58) | ALDH1A1ADRA2AHPGDNPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |