Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.61 |
| ▸ | APP | P05067 | 7/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | AQP1 | P29972 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8901980 | 0.99 | NPY5R (0.60) | NPY5RAPPBCHEACHENPC1 | |
| SCHEMBL8892223 | 0.90 | NPY5R (0.59) | NPY5RAPPBCHEACHENPC1 | |
| Hydrochloric Acid SCHEMBL8898597 | 0.88 | NPY5R (0.58) | NPY5RAPPBCHEACHENPC1 | |
| SCHEMBL13793109 | 0.86 | APP (0.52) | NPY5RAPPBCHEACHETSHR | |
| SCHEMBL13793836 | 0.86 | APP (0.52) | NPY5RAPPBCHEACHETSHR | |
| SCHEMBL2636281 | 0.84 | NPY5R (0.64) | NPY5RAPPAQP1ALDH1A1ADRA2A | |
| SCHEMBL8892212 | 0.84 | NPY5R (0.59) | NPY5RAPPBCHEACHENPC1 | |
| SCHEMBL3940588 | 0.83 | BCHE (0.58) | NPY5RAPPBCHEACHEWHR1 | |
| SCHEMBL3949263 | 0.83 | BCHE (0.58) | NPY5RAPPBCHEACHEWHR1 | |
| SCHEMBL11735631 | 0.83 | NPY5R (0.64) | NPY5RAPPBCHEACHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |