Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011395 | 0.86 | ALOX15 (0.51) | ALOX15ALDH1A1GAAMAPTTSHR | |
| SCHEMBL16653579 | 0.82 | ALOX15 (0.54) | ALOX15ALDH1A1GAAMAPTTSHR | |
| SCHEMBL7771034 | 0.82 | GAA (0.69) | ALDH1A1GAAMAPTTSHRPKM | |
| SCHEMBL16653372 | 0.78 | ALOX15 (0.50) | ALOX15ALDH1A1GAAMAPTTSHR | |
| SCHEMBL11191041 | 0.78 | ALOX15 (0.56) | ALOX15ALDH1A1GAATSHRMEN1 | |
| SCHEMBL9527006 | 0.76 | ALOX15 (0.54) | ALOX15ALDH1A1GAATSHRMEN1 | |
| SCHEMBL11191103 | 0.76 | ALOX15 (0.54) | ALOX15ALDH1A1GAATSHRMEN1 | |
| SCHEMBL12496081 | 0.75 | ALOX15 (0.53) | ALOX15ALDH1A1GAAMAPTTSHR | |
| SCHEMBL5203267 | 0.75 | ALOX15 (0.53) | ALOX15ALDH1A1GAAMAPTTSHR | |
| SCHEMBL7014898 | 0.74 | MAPT (0.58) | ALDH1A1GAAMAPTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |