Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892357 | 0.91 | MAP2K1 (0.33) | SMN1; SMN2ALDH1A1MEN1KMT2AMAP2K1 | |
| SCHEMBL8892368 | 0.91 | MAP2K1 (0.33) | SMN1; SMN2ALDH1A1MEN1KMT2AMAP2K1 | |
| SCHEMBL8892289 | 0.86 | MAP2K1 (0.35) | SMN1; SMN2MEN1KMT2AMAP2K1LTA4H | |
| SCHEMBL8901043 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1MEN1KMT2AMAP2K1 | |
| SCHEMBL8817699 | 0.73 | CCR6 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8817690 | 0.73 | CCR6 (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8725799 | 0.69 | MAPT (0.32) | ALDH1A1MAPTHPGD | |
| SCHEMBL8491834 | 0.69 | KMT2A (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8491832 | 0.69 | KMT2A (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8211416 | 0.68 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1MAPTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |