Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892409 | 0.88 | HCRTR2 (0.34) | HTTNPC1NPSR1RAB9AALDH1A1 | |
| SCHEMBL8890606 | 0.86 | HTT (0.37) | HTTSLC26A6NPC1NPSR1KMT2A | |
| SCHEMBL8890786 | 0.85 | HTT (0.36) | HTTSLC26A6NPC1NPSR1KMT2A | |
| SCHEMBL8890586 | 0.84 | ALDH1A1 (0.37) | HTTSLC26A6NPSR1ALDH1A1HCRTR2 | |
| SCHEMBL8890654 | 0.83 | HTT (0.34) | HTTNPSR1ALDH1A1HCRTR2TSHR | |
| SCHEMBL8891315 | 0.83 | HTT (0.40) | HTTNPSR1KMT2AALDH1A1HCRTR2 | |
| SCHEMBL8890880 | 0.82 | SLC6A2 (0.41) | HTTNPSR1KMT2APOLBALDH1A1 | |
| SCHEMBL8892752 | 0.81 | ALDH1A1 (0.38) | HTTNPC1NPSR1KMT2ARAB9A | |
| SCHEMBL9115212 | 0.81 | TSHR (0.35) | HTTSLC26A6ALDH1A1HCRTR2TSHR | |
| SCHEMBL8592076 | 0.80 | MEN1 (0.35) | HTTNPC1NPSR1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |