Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | GRB2 | P62993 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | TPH1 | P17752 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436718 | 0.96 | SLC1A3 (0.54) | PPARAPPARGEPHX2GRB2SLC1A3 | |
| SCHEMBL7436710 | 0.96 | SLC1A3 (0.54) | PPARAPPARGEPHX2GRB2SLC1A3 | |
| SCHEMBL7434968 | 0.95 | PPARA (0.46) | PPARAPPARGEPHX2GRB2SLC1A3 | |
| SCHEMBL8894789 | 0.95 | PPARA (0.46) | PPARAPPARGEPHX2GRB2SLC1A3 | |
| SCHEMBL7434959 | 0.95 | PPARA (0.46) | PPARAPPARGEPHX2GRB2SLC1A3 | |
| SCHEMBL2266372 | 0.84 | SLC1A3 (0.67) | PPARAPPARGEPHX2GRB2SLC1A3 | |
| SCHEMBL12762359 | 0.84 | SLC1A3 (0.67) | PPARAPPARGEPHX2GRB2SLC1A3 | |
| SCHEMBL7434194 | 0.84 | SLC1A3 (0.50) | PPARAPPARGSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7434192 | 0.84 | SLC1A3 (0.50) | PPARAPPARGSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7441434 | 0.84 | GRB2 (0.48) | PPARAPPARGEPHX2GRB2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |