Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.58 |
| ▸ | LIPC | P11150 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333003 | 0.93 | LIPG (0.55) | LIPGLIPCBRD4LMNACRBN | |
| SCHEMBL8912311 | 0.89 | LIPG (0.67) | LIPGLIPCKDM4EALOX5TSHR | |
| SCHEMBL6858842 | 0.89 | LIPG (0.67) | LIPGLIPCBRD4KDM4EALOX5 | |
| SCHEMBL6865227 | 0.88 | LIPG (0.65) | LIPGLIPCLMNAKDM4EALOX5 | |
| SCHEMBL19577104 | 0.88 | LIPG (0.58) | LIPGLIPCBRD4LMNACRBN | |
| SCHEMBL29785646 | 0.88 | LIPG (0.58) | LIPGLIPCBRD4ALOX5ALDH1A1 | |
| SCHEMBL6862929 | 0.88 | LIPG (0.58) | LIPGLIPCBRD4ALOX5ALDH1A1 | |
| SCHEMBL7043047 | 0.88 | LIPG (0.65) | LIPGLIPCLMNAKDM4EALOX5 | |
| SCHEMBL13339886 | 0.86 | LIPG (0.57) | LIPGLIPCBRD4LMNACRBN | |
| SCHEMBL8334416 | 0.85 | LIPG (0.62) | LIPGLIPCLMNAALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624901-A | CARBAMOYL SUBSTITUTED COMPOUNDS FOR CHELATE COMPOUNDS FOR MAGNETIC RESONANCE IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-04-29 | — | — | US | disclosed |