Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.42 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.42 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.42 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.42 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891354 | 0.91 | GUCY1B2 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8900822 | 0.88 | GUCY1B2 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8892306 | 0.81 | GUCY1B2 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8893747 | 0.78 | GUCY1B2 (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14761953 | 0.76 | KDM4E (0.58) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2301817 | 0.74 | RXFP1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7347964 | 0.72 | GUCY1B2 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31399941 | 0.71 | CYP1A2 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1259501 | 0.71 | CYP1A2 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2302821 | 0.71 | RXFP1 (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |