Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.48 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.48 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.48 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891354 | 0.92 | GUCY1B2 (0.45) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1RXFP1 | |
| SCHEMBL8892385 | 0.88 | MEN1 (0.45) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1RXFP1 | |
| SCHEMBL8892306 | 0.87 | GUCY1B2 (0.50) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1RXFP1 | |
| SCHEMBL8893747 | 0.84 | GUCY1B2 (0.47) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1RXFP1 | |
| SCHEMBL2301817 | 0.81 | RXFP1 (0.67) | RXFP1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8890570 | 0.79 | PGK1 (0.48) | RXFP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7347964 | 0.79 | GUCY1B2 (0.55) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1MEN1 | |
| SCHEMBL3578944 | 0.78 | RXFP1 (0.62) | RXFP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL31399941 | 0.78 | CYP1A2 (0.55) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1MEN1 | |
| SCHEMBL1259501 | 0.78 | CYP1A2 (0.55) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |