SCHEMBL8892632

SCHEMBL8892632

CCCCOC(=O)/C=C/C(=O)OOOC(C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.65
HCAR2 Q8TDS4 5/20 0.57
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TSHR P16473 2/20 0.47
HPGD P15428 1/20 0.47
APP P05067 5/20 0.40
ALDH1A1 P00352 1/20 0.40
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8892638 1.00 ATM (0.65) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9245719 0.95 HCAR2 (0.58) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9245726 0.95 HCAR2 (0.58) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9240625 0.94 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9244681 0.94 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9243239 0.94 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9244457 0.94 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9244689 0.94 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9244445 0.94 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9243244 0.94 HCAR2 (0.59) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997003962-A1 IMIDO PERESTERS AS INITIATORS OF POLYMERIZATION PROCESSES AKZO NOBEL N.V. (NL) 1997-02-06 WO disclosed
EP-0656911-B1 PROCESS FOR THE MODIFICATION OF ALPHA-OLEFIN (CO)POLYMERS AKZO NOBEL NV (NL) 1996-09-11 EP disclosed
EP-0656911-A1 PROCESS FOR THE MODIFICATION OF -g(a)-OLEFIN (CO)POLYMERS. AKZO NOBEL NV (NL) 1995-06-14 EP disclosed
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP disclosed
EP-0433046-B1 Polymer-type polymerization initiator TOMEI SANGYO KK (JP) 1994-08-10 EP disclosed
WO-1994005707-A1 PROCESS FOR THE MODIFICATION OF α-OLEFIN (CO)POLYMERS AKZO NOBEL N.V. (NL) 1994-03-17 WO disclosed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US disclosed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US disclosed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US disclosed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP disclosed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP disclosed