Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890411 | 0.91 | TSHR (0.34) | HTTNPSR1TSHRCDK2CCNE1 | |
| SCHEMBL9117063 | 0.87 | HTT (0.42) | HTTTHRBNPSR1MEN1HPGD | |
| SCHEMBL8491672 | 0.87 | HTT (0.42) | HTTTHRBNPSR1MEN1HPGD | |
| SCHEMBL8891083 | 0.86 | HTT (0.40) | HTTTHRBNPSR1MEN1HPGD | |
| SCHEMBL8891315 | 0.86 | HTT (0.40) | HTTTHRBNPSR1MEN1HPGD | |
| SCHEMBL8892762 | 0.85 | HCRTR2 (0.33) | HTTNPSR1TSHRCDK2CCNE1 | |
| SCHEMBL8890325 | 0.84 | HTT (0.34) | HTTNPSR1TSHRCDK2CCNE1 | |
| SCHEMBL8493474 | 0.83 | TSHR (0.37) | HTTTSHRMAPTALDH1A1LMNA | |
| SCHEMBL8907391 | 0.82 | HTT (0.42) | HTTTHRBNPSR1MEN1HPGD | |
| SCHEMBL8891900 | 0.82 | TSHR (0.39) | NPSR1TSHRCDK2CCNE1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |