Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892752 | 0.91 | ALDH1A1 (0.38) | HTTSLC6A2SLC6A4NPSR1ALDH1A1 | |
| SCHEMBL8491672 | 0.87 | HTT (0.42) | HTTPTGDR2THRBNPSR1ALDH1A1 | |
| SCHEMBL8891315 | 0.87 | HTT (0.40) | HTTPTGDR2THRBNPSR1ALDH1A1 | |
| SCHEMBL8892755 | 0.86 | HTT (0.39) | HTTPTGDR2THRBNPSR1ALDH1A1 | |
| SCHEMBL8890952 | 0.84 | ALDH1A1 (0.33) | HTTSLC6A2SLC6A4NPSR1ALDH1A1 | |
| SCHEMBL8907391 | 0.83 | HTT (0.42) | HTTPTGDR2THRBNPSR1ALDH1A1 | |
| SCHEMBL8892822 | 0.83 | HTT (0.34) | HTTNPSR1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8890538 | 0.83 | MAPT (0.35) | HTTSLC6A2SLC6A4NPSR1ALDH1A1 | |
| SCHEMBL8891811 | 0.82 | MAPT (0.38) | SLC6A2SLC6A4NPSR1ALDH1A1HPGD | |
| SCHEMBL8491704 | 0.82 | HTT (0.41) | HTTPTGDR2THRBNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |