Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.71 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.71 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.71 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.71 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.71 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.71 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.71 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.71 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6215029 | 0.91 | GRIN2B (0.85) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| Hydrochloric Acid SCHEMBL467351 | 0.88 | GRIN1 (0.68) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| Hydrochloric Acid SCHEMBL7248616 | 0.83 | GRIN2B (0.55) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL27447538 | 0.81 | GRIN2B (0.69) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL6011652 | 0.79 | SLC6A4 (0.62) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL5777439 | 0.79 | SLC6A4 (0.59) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL5950353 | 0.79 | SLC6A4 (0.59) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL6011653 | 0.79 | SLC6A4 (0.62) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL8814813 | 0.78 | GRIN2D (0.69) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D | |
| SCHEMBL6705234 | 0.78 | CCR5 (0.85) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997009310-A1 | 1-PHENYL-3-4-[BENZYLPIPERIDINYL-1]-PROPANOL-1 DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL APPLICATION THEREOF | SYNTHELABO (FR) | 1997-03-13 | — | — | WO | disclosed |