Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27798357 | 0.84 | SIGMAR1 (0.62) | GAACYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL6749044 | 0.82 | CYP2D6 (0.57) | GAACYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL26086670 | 0.81 | GAA (0.54) | GAACYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL26086748 | 0.77 | CYP2D6 (0.48) | GAACYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL23727894 | 0.77 | SIGMAR1 (0.54) | GAACYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL31230946 | 0.77 | CYP2D6 (0.61) | GAACYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL3464617 | 0.77 | CYP2D6 (0.61) | GAACYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL14089988 | 0.76 | MC4R (0.58) | GAACYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL17706684 | 0.76 | SIGMAR1 (0.52) | GAACYP2D6MEN1KMT2AUSP2 | |
| SCHEMBL31230966 | 0.76 | CYP2D6 (0.59) | GAACYP2D6MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |