Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.66 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.58 |
| ▸ | TNF | P01375 | 2/20 | 0.56 |
| ▸ | MDM4 | O15151 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445595 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 | |
| SCHEMBL29445602 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 | |
| SCHEMBL31398320 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 | |
| SCHEMBL17749229 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 | |
| SCHEMBL15083321 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 | |
| SCHEMBL20357051 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 | |
| SCHEMBL16744148 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 | |
| SCHEMBL16744151 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 | |
| SCHEMBL18614182 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 | |
| SCHEMBL29615002 | 1.00 | TLR2 (0.66) | TLR2MDM2TNFMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | UNIV MONASH (AU) | 2015-05-28 | — | — | US | disclosed |
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | UNIV MONASH (AU) | 2015-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | DAO, BCAT2, BCAT1 | TLR2 3179/4885MDM2 216/4885TNF 4203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.