Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363823 | 0.84 | HDAC6 (0.46) | MAOBMAOAHDAC6RAB9AKMT2A | |
| SCHEMBL10362189 | 0.83 | HDAC6 (0.48) | MAOBMAOAHDAC6RAB9AMEN1 | |
| SCHEMBL2208757 | 0.83 | HDAC6 (0.60) | MAOBMAOAHTR2CPTPRCPTPN1 | |
| SCHEMBL21480315 | 0.83 | MAOB (0.57) | MAOBMAOAHTR2CPTPRCPTPN1 | |
| SCHEMBL21480331 | 0.83 | MAOB (0.57) | MAOBMAOAHTR2CPTPRCPTPN1 | |
| SCHEMBL4901772 | 0.83 | MAOB (0.57) | MAOBMAOAHTR2CPTPRCPTPN1 | |
| SCHEMBL18015826 | 0.83 | MAOB (0.57) | MAOBMAOAHTR2CPTPRCPTPN1 | |
| SCHEMBL12854020 | 0.79 | MAOB (0.71) | MAOBMAOAHTR2CPTPRCPTPN1 | |
| SCHEMBL61411 | 0.79 | MAOB (0.71) | MAOBMAOAHTR2CPTPRCPTPN1 | |
| SCHEMBL18014705 | 0.79 | MAOB (0.53) | MAOBMAOAHTR2CPTPRCPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023466-A1 | NOVEL COMPOUNDS WITH ANALGESIC EFFECT | ASTRA PHARMA INC. (CA) | 1997-07-03 | — | — | WO | disclosed |
| US-4800208-A | (Benzofuran-2-yl)imidazoles having pharmaceutical activity, their salts and relevant production processes | A. MENARINI S.A.S. (IT) | 1989-01-24 | — | — | US | disclosed |
| EP-0257171-A1 | (Benzofuran-2-yl)imidazoles having pharmaceutical activity, their salts and relevant production processes | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1988-03-02 | — | — | EP | disclosed |