Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362748 | 0.85 | HDAC6 (0.64) | HDAC6MAOBMAOANPC1RAB9A | |
| SCHEMBL10363823 | 0.84 | HDAC6 (0.46) | HDAC6MAOBMAOANPC1RAB9A | |
| SCHEMBL8893064 | 0.83 | MAOB (0.57) | HDAC6MAOBMAOANPC1RAB9A | |
| SCHEMBL11106881 | 0.75 | ALDH1A1 (0.46) | HDAC6MAOBMAOANPC1RAB9A | |
| SCHEMBL10694386 | 0.75 | CYP19A1 (0.63) | ADRA2C | |
| SCHEMBL14231754 | 0.75 | NPC1 (0.61) | MAOBMAOANPC1RAB9AADRA2A | |
| Hydrochloric Acid SCHEMBL10537534 | 0.74 | CYP19A1 (0.62) | ADRA2C | |
| SCHEMBL8179409 | 0.73 | MAOB (0.48) | MAOBMAOANPC1RAB9AADRA2A | |
| SCHEMBL20473374 | 0.73 | MAOB (0.46) | HDAC6MAOBMAOAGABRPGABRD | |
| SCHEMBL30568042 | 0.73 | MAOB (0.46) | HDAC6MAOBMAOAGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257171-B1 | (BENZOFURAN-2-YL)IMIDAZOLES HAVING PHARMACEUTICAL ACTIVITY, THEIR SALTS AND RELEVANT PRODUCTION PROCESSES | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1990-08-29 | — | — | EP | disclosed |
| US-4800208-A | (Benzofuran-2-yl)imidazoles having pharmaceutical activity, their salts and relevant production processes | A. MENARINI S.A.S. (IT) | 1989-01-24 | — | — | US | disclosed |
| EP-0257171-A1 | (Benzofuran-2-yl)imidazoles having pharmaceutical activity, their salts and relevant production processes | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1988-03-02 | — | — | EP | disclosed |