Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.33 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852724 | 1.00 | PIK3CD (0.36) | PIK3CDALDH1A1KAT2BBAZ2BPDE4D | |
| SCHEMBL8692875 | 1.00 | PIK3CD (0.36) | PIK3CDALDH1A1KAT2BBAZ2BPDE4D | |
| SCHEMBL18787636 | 0.89 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL1811324 | 0.89 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL1811325 | 0.89 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL1813149 | 0.89 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL18787734 | 0.89 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL26940404 | 0.85 | — | — | |
| SCHEMBL29224614 | 0.85 | — | — | |
| SCHEMBL29224615 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |