Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 16/20 | 0.39 |
| ▸ | PDE4A | P27815 | 9/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811324 | 1.00 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL1813149 | 1.00 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL18787636 | 1.00 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL18787734 | 1.00 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL8852724 | 0.89 | PIK3CD (0.36) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL8692875 | 0.89 | PIK3CD (0.36) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL8893225 | 0.89 | PIK3CD (0.36) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL1810905 | 0.80 | CYP3A4 (0.37) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL1810901 | 0.80 | CYP3A4 (0.37) | PDE4DPDE4APDE4BPDE4CACACB | |
| SCHEMBL14364761 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055846-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-02-20 | — | — | US | disclosed |
| US-20200055846-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2020-02-20 | — | — | US | disclosed |
| US-10442808-B2 | Pyrazolo pyrimidine derivatives and their use as MALT1 inhbitors | NOVARTIS AG (CH) | 2019-10-15 | — | — | US | disclosed |
| EP-3149001-B1 | NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES AND THEIR USE AS MALT1 INHIBITORS | NOVARTIS AG (CH) | 2019-04-24 | — | — | EP | disclosed |
| US-10165775-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-10165775-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-20180030061-A1 | NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES AND THEIR USE AS MALT1 INHBITORS | NOVARTIS AG (CH) | 2018-02-01 | — | — | US | disclosed |
| US-9815842-B2 | Pyrazolo pyrimidine derivatives and their use as MALT1 inhibitors | NOVARTIS AG (CH) | 2017-11-14 | — | — | US | disclosed |
| US-20170267657-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-09-21 | — | — | US | disclosed |
| US-20170267657-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-09-21 | — | — | US | disclosed |
| US-20130109566-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109566-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2013062981-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2013062981-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2012061290-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012061290-A2 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2012-05-10 | — | — | WO | disclosed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | disclosed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | disclosed |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | CORTEVA AGRISCIENCE LLC | 2012-05-03 | — | — | US | disclosed |
| WO-2011061590-A1 | NOVEL CARBOXAMIDE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109566-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | PDE4D 369/4885PDE4A 259/4885PDE4B 196/4885 |
| US-20180030061-A1 | NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES AND THEIR USE AS MALT1 INHBITORS | MMEL1, MALT1, FBP1 | PDE4D 2447/4885PDE4A 2492/4885PDE4B 2402/4885 |
| US-20200055846-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | PDE4D 369/4885PDE4A 259/4885PDE4B 196/4885 |
| US-20170267657-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | PDE4D 369/4885PDE4A 259/4885PDE4B 196/4885 |
| US-10442808-B2 | Pyrazolo pyrimidine derivatives and their use as MALT1 inhbitors | FBP1, MMEL1, MALT1 | PDE4D 2550/4885PDE4A 2269/4885PDE4B 2233/4885 |
| US-10165775-B2 | Pesticidal compositions and processes related thereto | ACHE, DDT, PTMS | PDE4D 369/4885PDE4A 259/4885PDE4B 196/4885 |
| US-20120110702-A1 | Pesticidal Compositions and Processes Related Thereto | ACHE, DDT, PTMS | PDE4D 369/4885PDE4A 259/4885PDE4B 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.