Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385155 | 0.87 | HMGCR (0.44) | HMGCRTSHRPTPN7 | |
| SCHEMBL8806187 | 0.84 | — | — | |
| SCHEMBL5655040 | 0.84 | TSHR (0.36) | HMGCRTSHR | |
| SCHEMBL4763127 | 0.81 | HMGCR (0.33) | HMGCRTSHR | |
| SCHEMBL5166947 | 0.79 | — | — | |
| SCHEMBL56364 | 0.78 | — | — | |
| SCHEMBL5166944 | 0.78 | — | — | |
| SCHEMBL1533719 | 0.77 | HMGCR (0.42) | HMGCRTSHRPTPN7 | |
| SCHEMBL2571403 | 0.77 | TSHR (0.38) | HMGCRTSHRPTPN7 | |
| SCHEMBL3030008 | 0.76 | HMGCR (0.49) | HMGCRTSHRPTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043255-A1 | INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-11-20 | — | — | WO | disclosed |