Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 11/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893422 | 1.00 | KMT2A (0.49) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL13256879 | 0.89 | ESRRA (0.40) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL13256873 | 0.88 | PTPN1 (0.41) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL13256853 | 0.86 | HPGD (0.57) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL7829571 | 0.86 | HPGD (0.57) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL8893199 | 0.85 | MAPT (0.40) | KMT2AMEN1PTPN1TDP1 | |
| SCHEMBL8895476 | 0.83 | MEN1 (0.36) | KMT2AMEN1TDP1 | |
| SCHEMBL13256876 | 0.81 | GSK3B (0.40) | KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL7836724 | 0.80 | MEN1 (0.47) | KMT2AMEN1ALDH1A1POLBKDM4E | |
| SCHEMBL7134832 | 0.80 | KMT2A (0.41) | KMT2AMEN1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043284-A1 | NEW THIAZOLIDINEDIONES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |