Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924748 | 0.89 | MEN1 (0.38) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL8893417 | 0.85 | KMT2A (0.49) | MEN1KMT2ATDP1PTPN1 | |
| SCHEMBL8893422 | 0.85 | KMT2A (0.49) | MEN1KMT2ATDP1PTPN1 | |
| SCHEMBL8895476 | 0.84 | MEN1 (0.36) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL7838082 | 0.82 | MEN1 (0.49) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL11601582 | 0.80 | PSEN1 (0.42) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL11601587 | 0.80 | PSEN1 (0.42) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL7969326 | 0.80 | PSEN1 (0.42) | MAPTMEN1KMT2ATDP1PPARG | |
| SCHEMBL8485403 | 0.80 | HTR1A (0.41) | MAPTMEN1KMT2ATDP1ALOX5 | |
| SCHEMBL8893793 | 0.79 | MEN1 (0.39) | MAPTMEN1KMT2ATDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043284-A1 | NEW THIAZOLIDINEDIONES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |