Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926278 | 0.83 | POLB (0.50) | KDM4EALDH1A1TSHRLMNAHPGD | |
| SCHEMBL4732713 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1TSHRTDP1MDM4 | |
| SCHEMBL5928724 | 0.80 | TSHR (0.68) | KDM4EALDH1A1TSHRTDP1MDM4 | |
| SCHEMBL31514070 | 0.79 | CA12 (0.59) | KDM4EALDH1A1TSHRTP53LMNA | |
| SCHEMBL14058702 | 0.78 | NPC1 (0.57) | KDM4EALDH1A1TDP1MDM4TP53 | |
| SCHEMBL1663385 | 0.78 | CA12 (0.59) | KDM4EALDH1A1TSHRTDP1MDM4 | |
| SCHEMBL20819619 | 0.77 | MDM4 (0.51) | KDM4EALDH1A1MDM4TP53L3MBTL1 | |
| SCHEMBL26886813 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1TSHRTDP1MDM4 | |
| SCHEMBL26885008 | 0.76 | TP53 (0.50) | KDM4EALDH1A1MDM4TP53L3MBTL1 | |
| SCHEMBL8669428 | 0.76 | CA1 (0.55) | KDM4EALDH1A1TSHRLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997047589-A1 | AMINOPHTHALIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-18 | — | — | WO | disclosed |