Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928724 | 0.83 | TSHR (0.68) | KDM4EALDH1A1LMNATSHRTDP1 | |
| SCHEMBL8893471 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1LMNATSHRTDP1 | |
| SCHEMBL4732717 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1LMNATSHRTDP1 | |
| SCHEMBL31590548 | 0.76 | LMNA (0.53) | KDM4EALDH1A1LMNATSHRHPGD | |
| SCHEMBL4026343 | 0.76 | LMNA (0.53) | KDM4EALDH1A1LMNATSHRHPGD | |
| SCHEMBL8908317 | 0.74 | POLB (0.50) | KDM4EALDH1A1LMNATSHRHPGD | |
| SCHEMBL16281636 | 0.74 | MDM4 (0.51) | KDM4EALDH1A1LMNAMDM4TP53 | |
| SCHEMBL19955442 | 0.74 | MAOA (0.46) | KDM4EALDH1A1LMNATSHRHPGD | |
| SCHEMBL6164745 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1LMNATSHRTDP1 | |
| SCHEMBL1663385 | 0.72 | CA12 (0.59) | KDM4EALDH1A1TSHRTDP1MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008054454-A2 | NITROGEN-CONTAINING HETEROCYCLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF AS ANTIVIRAL AGENTS | TRANSTECH PHARMA, INC. (US) | 2008-05-08 | — | — | WO | disclosed |