Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2430213 | 0.84 | TSHR (0.46) | EPHX1LMNAATMHPGDTSHR | |
| SCHEMBL7063313 | 0.81 | EPHX1 (0.50) | EPHX1LMNAATMCES1HCAR2 | |
| SCHEMBL7063306 | 0.81 | EPHX1 (0.50) | EPHX1LMNAATMCES1HCAR2 | |
| SCHEMBL6408698 | 0.78 | EPHX1 (0.47) | EPHX1LMNAHPGDTSHR | |
| SCHEMBL28411292 | 0.78 | EPHX1 (0.50) | EPHX1LMNATSHRCES1 | |
| SCHEMBL10426941 | 0.74 | TSHR (0.42) | EPHX1HPGDTSHR | |
| SCHEMBL10427254 | 0.74 | TSHR (0.42) | EPHX1HPGDTSHR | |
| SCHEMBL8424510 | 0.74 | EPHX1 (0.55) | EPHX1LMNACES1 | |
| SCHEMBL2432692 | 0.74 | TSHR (0.43) | EPHX1LMNATSHR | |
| SCHEMBL10763267 | 0.73 | EPHX1 (0.58) | EPHX1LMNATSHRCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |