Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063313 | 1.00 | EPHX1 (0.50) | EPHX1MAPTGMNNTP53POLB | |
| SCHEMBL6408698 | 0.87 | EPHX1 (0.47) | EPHX1MAPTGMNNTP53POLB | |
| SCHEMBL8424510 | 0.84 | EPHX1 (0.55) | EPHX1MAPTGMNNTP53POLB | |
| SCHEMBL8426321 | 0.82 | EPHX1 (0.53) | EPHX1MAPTGMNNTP53POLB | |
| SCHEMBL8893585 | 0.81 | EPHX1 (0.40) | EPHX1HCAR2LMNAATMCES1 | |
| SCHEMBL10624263 | 0.81 | EPHX1 (0.51) | EPHX1MAPTGMNNTP53POLB | |
| SCHEMBL2430213 | 0.79 | TSHR (0.46) | EPHX1MAPTTHRBLMNAATM | |
| SCHEMBL10763267 | 0.79 | EPHX1 (0.58) | EPHX1MAPTGMNNTP53POLB | |
| SCHEMBL7646476 | 0.77 | TSHR (0.49) | EPHX1MAPTGMNNTP53POLB | |
| SCHEMBL10426941 | 0.77 | TSHR (0.42) | EPHX1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593263-B1 | Lubricants, greases, aqueous fluids and concentrates containing additives derived from dimercaptothiadiazoles | LUBRIZOL CORP (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-0593263-A1 | Lubricants, greases, aqueous fluids and concentrates containing additives derived from dimercaptothiadiazoles | The Lubrizol Corporation (US) | 1994-04-20 | — | — | EP | disclosed |