SCHEMBL8893668

SCHEMBL8893668

COc1ccccc1OCCl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
CA4 P22748 1/20 0.62
CA7 P43166 1/20 0.62
CA9 Q16790 1/20 0.62
CA14 Q9ULX7 1/20 0.62
SMN1; SMN2 Q16637 3/20 0.53
POLB P06746 1/20 0.53
L3MBTL1 Q9Y468 4/20 0.53
TDP1 Q9NUW8 1/20 0.52
LMNA P02545 3/20 0.50
APP P05067 1/20 0.50
AGTR1 P30556 1/20 0.50
CYP1A2 P05177 1/20 0.50
MAPK1 P28482 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HTT P42858 1/20 0.48
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7690167 0.87 KDM4E (0.46) CA12CA1CA2CA4CA7
1,2-Dimethoxybenzene SCHEMBL27639335 0.85 CA1 (0.77) CA12CA1CA2CA4CA7
SCHEMBL30960112 0.82 L3MBTL1 (0.59) CA12CA1CA2CA4CA7
SCHEMBL4427769 0.82 L3MBTL1 (0.59) CA12CA1CA2CA4CA7
SCHEMBL1545294 0.82 L3MBTL1 (0.63) CA12CA1CA2CA4CA7
SCHEMBL5659890 0.80 L3MBTL1 (0.67) CA12CA1CA2CA4CA7
Water SCHEMBL10556855 0.80 L3MBTL1 (0.61) CA12CA1CA2CA4CA7
SCHEMBL1592409 0.80 CA12 (0.68) CA12CA1CA2CA4CA7
SCHEMBL11364617 0.80 CA1 (0.68) CA12CA1CA2CA4CA7
1,2-Dimethoxybenzene SCHEMBL29351917 0.79 CA1 (1.00) CA12CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2508504-B1 PROCESS FOR PREPARATION OF CYCLOALKANEDICARBOXYLIC ACID MONOESTERS SUMITOMO CHEMICAL CO (JP) 2016-04-13 EP disclosed
CN-102686551-B Process for producing cycloalkanedicarboxylic acid monoester SUMITOMO CHEMICAL CO 2014-11-12 CN disclosed
EP-2508504-A1 PROCESS FOR PREPARATION OF CYCLOALKANEDICARBOXYLIC ACID MONOESTERS Sumitomo Chemical Co., Ltd (JP) 2012-10-10 EP disclosed
WO-1997041109-A1 SYNTHESIS OF (±) - CALICHEAMICINONE, PRECURSORS, INTERMEDIATES AND DERIVATIVES UNIVERSITY OF ALBERTA (CA) 1997-11-06 WO disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed