Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723016 | 0.81 | IDO1 (0.49) | IDO1ADRA2AADRA1ACYP2D6LMNA | |
| SCHEMBL1567118 | 0.81 | IDO1 (0.49) | IDO1ADRA2AADRA1ACYP2D6LMNA | |
| SCHEMBL9159890 | 0.81 | IDO1 (0.49) | IDO1CYP2D6LMNAHTTALDH1A1 | |
| SCHEMBL8699708 | 0.81 | IDO1 (0.49) | IDO1CYP2D6LMNAHTTALDH1A1 | |
| SCHEMBL29663637 | 0.81 | IDO1 (0.49) | IDO1CYP2D6LMNAHTTALDH1A1 | |
| SCHEMBL782544 | 0.81 | IDO1 (0.49) | IDO1CYP2D6LMNAHTTALDH1A1 | |
| SCHEMBL10648765 | 0.80 | IDO1 (0.45) | IDO1ADRA2AADRA1ACYP2D6LMNA | |
| SCHEMBL7576444 | 0.79 | SMN1; SMN2 (0.51) | IDO1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7576452 | 0.79 | SMN1; SMN2 (0.51) | IDO1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL361005 | 0.78 | IDO1 (0.46) | IDO1ADRA2AADRA1ACYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |