Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576452 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2IDO1HTTKDM1ARAB9A | |
| SCHEMBL8893702 | 0.79 | IDO1 (0.49) | SMN1; SMN2IDO1HTTMEN1KMT2A | |
| SCHEMBL6723016 | 0.75 | IDO1 (0.49) | IDO1HTT | |
| SCHEMBL1567118 | 0.75 | IDO1 (0.49) | IDO1HTT | |
| SCHEMBL9159890 | 0.75 | IDO1 (0.49) | SMN1; SMN2IDO1HTTMEN1KMT2A | |
| SCHEMBL782544 | 0.75 | IDO1 (0.49) | SMN1; SMN2IDO1HTTMEN1KMT2A | |
| SCHEMBL8699708 | 0.75 | IDO1 (0.49) | SMN1; SMN2IDO1HTTMEN1KMT2A | |
| SCHEMBL29663637 | 0.75 | IDO1 (0.49) | SMN1; SMN2IDO1HTTMEN1KMT2A | |
| SCHEMBL4948903 | 0.73 | SMN1; SMN2 (0.65) | SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL10643837 | 0.73 | ALDH1A1 (0.43) | SMN1; SMN2IDO1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020143062-A1 | Method to incorporate N-(4-hydroxyphenyl) retinamide in liposomes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-10-03 | — | — | US | disclosed |
| US-5055622-A | For treating neoplasms and dermatoses | HOFFMANN-LA ROCHE INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-5030764-A | Antitumor agents; treatment of skin disorders | HOFFMANN-LA ROCHE INC. (US) | 1991-07-09 | — | — | US | disclosed |
| US-5001276-A | Novel tetrahydronaphthalene and indane derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-03-19 | — | — | US | disclosed |
| US-4990703-A | Novel tetrahydronaphthalene and indane derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-02-05 | — | — | US | disclosed |
| US-4935560-A | ANTITUMOR AGENTS; SKIN DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1990-06-19 | — | — | US | disclosed |