Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893777 | 1.00 | SIRT2 (0.53) | SIRT2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28661703 | 0.80 | CYP1A2 (0.55) | SIRT2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4659586 | 0.78 | MEN1 (0.46) | SIRT2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13919659 | 0.78 | MEN1 (0.53) | SIRT2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8699920 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL9380861 | 0.74 | MEN1 (0.49) | SIRT2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL14161475 | 0.74 | HTR2A (0.57) | KMT2AMEN1LMNACYP1A2PKM | |
| SCHEMBL16360806 | 0.74 | MEN1 (0.51) | KMT2AMEN1LMNACYP1A2PKM | |
| SCHEMBL1753696 | 0.74 | HTR2A (0.61) | KMT2AMEN1LMNACYP1A2PKM | |
| SCHEMBL8892454 | 0.73 | KDM4E (0.49) | KMT2AMEN1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |