Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 13/20 | 0.78 |
| ▸ | HTR1B | P28222 | 11/20 | 0.78 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688690 | 0.88 | HTR1D (1.00) | HTR1DHTR1BMPOHTR1AHTR6 | |
| SCHEMBL8901244 | 0.81 | HTR1D (0.76) | HTR1DHTR1BHTR1A | |
| SCHEMBL8686120 | 0.81 | HTR1D (1.00) | HTR1DHTR1BMPOHTR1AHTR6 | |
| Hydrochloric Acid SCHEMBL7317904 | 0.80 | HTR1D (0.97) | HTR1DHTR1BMPOHTR1AHTR6 | |
| Dimethylamine SCHEMBL8688692 | 0.80 | HTR1D (0.67) | HTR1DHTR1B | |
| Diethylamine SCHEMBL8903599 | 0.78 | HTR1D (0.64) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL8902207 | 0.76 | HTR1D (0.64) | HTR1DHTR1BHTR1A | |
| SCHEMBL8686765 | 0.75 | HTR1D (1.00) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL1750009 | 0.75 | HTR1D (0.66) | HTR1DHTR1B | |
| SCHEMBL8902545 | 0.75 | HTR1D (1.00) | HTR1DHTR1BMPOHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | claimed |
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |