Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 12/20 | 0.64 |
| ▸ | HTR1B | P28222 | 12/20 | 0.64 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.44 |
| ▸ | TUBB | P07437 | 3/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901244 | 0.78 | HTR1D (0.76) | HTR1DHTR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL8686120 | 0.78 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL8688690 | 0.78 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR7 | |
| Dimethylamine SCHEMBL8688692 | 0.77 | HTR1D (0.67) | HTR1DHTR1BTUBB4ATUBBTUBA3C | |
| Hydrochloric Acid SCHEMBL7317904 | 0.77 | HTR1D (0.97) | HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL6280803 | 0.77 | HTR2A (0.58) | HTR1DHTR1BGFERHTR1AHTR7 | |
| SCHEMBL25307628 | 0.76 | MPO (0.60) | HTR1A | |
| SCHEMBL8893988 | 0.76 | HTR1D (0.78) | HTR1DHTR1BHTR1A | |
| Diethylamine SCHEMBL8903599 | 0.75 | HTR1D (0.64) | HTR1DHTR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL649226 | 0.75 | HTR2A (0.53) | HTR1DHTR1BHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |