Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280961 | 0.83 | POLB (0.68) | POLBKMT2ANPC1RAB9AMAOB | |
| SCHEMBL82673 | 0.83 | POLB (1.00) | POLBKMT2ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9177598 | 0.78 | HPGD (0.46) | POLBKMT2AAPPNPC1RAB9A | |
| SCHEMBL1053740 | 0.75 | POLB (0.54) | POLBKMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL12051091 | 0.75 | POLB (0.60) | POLBKMT2ALMNAGAAALDH1A1 | |
| SCHEMBL15670842 | 0.75 | POLB (0.41) | POLBKMT2AAPPNPC1RAB9A | |
| SCHEMBL9168285 | 0.75 | LMNA (0.73) | POLBKMT2AAPPNPC1RAB9A | |
| Glycerin SCHEMBL6953616 | 0.74 | POLB (0.80) | POLBKMT2ANPC1SMN1; SMN2LMNA | |
| SCHEMBL2454041 | 0.74 | POLB (0.63) | POLBKMT2ALMNAGAAMEN1 | |
| SCHEMBL92982 | 0.73 | POLB (0.58) | POLBKMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997032858-A1 | QUINOXALINE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-12 | — | — | WO | disclosed |