Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988865 | 0.97 | HDAC2 (0.50) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL4449518 | 0.95 | HDAC4 (0.48) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL3133166 | 0.82 | — | — | |
| SCHEMBL3133890 | 0.79 | — | — | |
| SCHEMBL2689130 | 0.78 | HDAC2 (0.47) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL310711 | 0.78 | — | — | |
| SCHEMBL1053257 | 0.78 | — | — | |
| SCHEMBL1054591 | 0.76 | HDAC4 (0.45) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL11038707 | 0.76 | HDAC2 (0.55) | HDAC2HDAC4HDAC8HDAC6HDAC1 | |
| SCHEMBL621702 | 0.76 | HDAC2 (0.55) | HDAC2HDAC4HDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343307-A1 | 4-Piperidinealkanamine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) | 1989-11-29 | — | — | EP | claimed |
| WO-1997027173-A2 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-31 | — | — | WO | disclosed |