SCHEMBL2689130

SCHEMBL2689130

CC(C)=C(C)C1=CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 3/20 0.47
HDAC4 P56524 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
CTSK P43235 1/20 0.42
HDAC3 O15379 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
CCR2 P41597 1/20 0.32
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9363245 0.93 HDAC4 (0.45) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL14988865 0.80 HDAC2 (0.50) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL3133166 0.80
SCHEMBL9128936 0.79 HDAC2 (0.50) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL8894092 0.78 HDAC2 (0.48) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL310711 0.76
SCHEMBL1053257 0.76
SCHEMBL2687386 0.74 HDAC4 (0.45) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL1054591 0.74 HDAC4 (0.45) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL621702 0.74 HDAC2 (0.55) HDAC2HDAC4HDAC8HDAC6CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168842-B2 Process for the alkylation of a cycloalkene SHELL OIL COMPANY (US) 2012-05-01 US disclosed
US-20090227824-A1 PROCESS FOR THE ALKYLATION OF A CYCLOALKENE SHELL OIL COMPANY 2009-09-10 US disclosed
WO-2007135047-A1 PROCESS FOR THE ALKYLATION OF A CYCLOALKENE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2007-11-29 WO disclosed
US-4568757-A ACNE, PSORIASIS, ANTITUMOR AGENTS, VITAMIN A TYPE ACTIVITY RESEARCH TRIANGLE INSTITUTE (US) 1986-02-04 US disclosed
US-4568757-A ACNE, PSORIASIS, ANTITUMOR AGENTS, VITAMIN A TYPE ACTIVITY RESEARCH TRIANGLE INSTITUTE (US) 1986-02-04 US disclosed