Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666267 | 0.78 | CCR1 (0.39) | KDM4ETDP1GRM5ALDH1A1TP53 | |
| SCHEMBL3408475 | 0.78 | NPC1 (0.37) | KDM4ETDP1GRM5ALDH1A1TP53 | |
| SCHEMBL30763450 | 0.78 | NPC1 (0.37) | KDM4ETDP1GRM5ALDH1A1TP53 | |
| SCHEMBL6629729 | 0.78 | KDM4E (0.35) | KDM4ETDP1ALDH1A1TP53HTR2C | |
| SCHEMBL3406541 | 0.78 | TP53 (0.46) | KDM4ETDP1GRM5ALDH1A1TP53 | |
| SCHEMBL8891318 | 0.77 | KDM4E (0.65) | KDM4ETDP1GRM5ALDH1A1TP53 | |
| SCHEMBL25493617 | 0.74 | TP53 (0.38) | KDM4ETDP1GRM5ALDH1A1TP53 | |
| SCHEMBL8891737 | 0.73 | KDM4E (0.41) | KDM4ETDP1GRM5ALDH1A1TP53 | |
| SCHEMBL14733153 | 0.73 | CCR1 (0.52) | GRM5 | |
| SCHEMBL28112949 | 0.71 | NPC1 (0.33) | KDM4EALDH1A1GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5626791-A | FERROELECTRIC LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |