Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25493617 | 0.86 | TP53 (0.38) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL27946276 | 0.84 | TP53 (0.37) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL1456807 | 0.81 | GOT1 (0.46) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL30792004 | 0.81 | GOT1 (0.46) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL29442588 | 0.81 | GOT1 (0.46) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL30686995 | 0.81 | GRM5 (0.39) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL322178 | 0.78 | KDM4E (0.70) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL31609343 | 0.78 | KDM4E (0.70) | TP53KDM4ELMNACCR1CCR5 | |
| SCHEMBL6629729 | 0.78 | KDM4E (0.35) | TP53KDM4EALOX15L3MBTL1TDP1 | |
| SCHEMBL8894101 | 0.78 | KDM4E (0.36) | TP53KDM4ENPC1RAB9AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194425-B1 | SUBSTITUTED BENZIMIDAZOLE | AVENTIS PHARMA GMBH (DE) | 2005-08-10 | — | — | EP | claimed |
| EP-3892617-B1 | FLUORINATED PYRIMIDINE COMPOUND AND PRODUCTION METHOD THEREFOR | UNIMATEC CO LTD (JP) | 2025-04-30 | — | — | EP | disclosed |
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | UNIMATEC CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
| US-20230331734-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-10-19 | — | — | US | disclosed |
| EP-3324977-B1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-13 | — | — | EP | disclosed |
| CN-112739689-B | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2022-06-03 | — | — | CN | disclosed |
| US-20210403455-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND METHOD FOR MANUFACTURING THE SAME | UNIMATEC CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
| EP-3892617-A1 | FLUORINATED PYRIMIDINE COMPOUND AND PRODUCTION METHOD THEREFOR | Unimatec Co., Ltd. (JP) | 2021-10-13 | — | — | EP | disclosed |
| CN-112739689-A | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2021-04-30 | — | — | CN | disclosed |
| US-10821433-B2 | Ion exchange resins, purification methods and methods of making ionic resins | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2020-11-03 | — | — | US | disclosed |
| WO-1999009032-A1 | CARBAPENEMS WITH NAPHTHOSULTAM DERIVATIVE LINKED VIA METHYLENE | MERCK & CO., INC. (US) | 1999-02-25 | — | — | WO | disclosed |
| WO-1998043651-A1 | MUR D INHIBITING COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 1998-10-08 | — | — | WO | disclosed |
| WO-1998010761-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 1998-03-19 | — | — | WO | disclosed |
| WO-1997040048-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 1997-10-30 | — | — | WO | disclosed |
| EP-0750620-A4 | CARBAPENEM COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT | MERCK & CO INC (US) | 1997-07-16 | — | — | EP | disclosed |
| US-5626791-A | FERROELECTRIC LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0750620-A1 | CARBAPENEM COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT | MERCK & CO. INC. (US) | 1997-01-02 | — | — | EP | disclosed |
| CN-1032239-C | Process for selective removal of inorganic and/or organic sulfur-containing compounds | UBE INDUSTRIES (JP) | 1996-07-10 | — | — | CN | disclosed |
| WO-1995025108-A1 | CARBAPENEM COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 1995-09-21 | — | — | WO | disclosed |
| CN-1063052-A | The method of selective removal of inorganic and/or sulfur-containing organic compound | UBE INDUSTRIES (JP) | 1992-07-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331734-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ACE, PKD1, ACE2 | TP53 1461/4885KDM4E 3466/4885LMNA 3483/4885 |
| US-12043615-B2 | Fluorine-containing pyrimidine compound and method for manufacturing the same | CNOT1, NUDT1, XRN2 | TP53 2258/4885KDM4E 4521/4885LMNA 2304/4885 |
| US-20210403455-A1 | FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND METHOD FOR MANUFACTURING THE SAME | CNOT1, NUDT1, XRN2 | TP53 2258/4885KDM4E 4521/4885LMNA 2304/4885 |
| US-10821433-B2 | Ion exchange resins, purification methods and methods of making ionic resins | TST, SLC6A9, TEX10 | TP53 3317/4885KDM4E 1279/4885LMNA 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.