Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29398667 | 0.98 | NOS2 (0.37) | NOS2NOS1NOS3TSHRALDH1A1 | |
| SCHEMBL210388 | 0.85 | NOS2 (0.49) | NOS2NOS1NOS3TSHRALDH1A1 | |
| SCHEMBL3928876 | 0.85 | NOS2 (0.49) | NOS2NOS1NOS3TSHRALDH1A1 | |
| SCHEMBL210387 | 0.85 | NOS2 (0.49) | NOS2NOS1NOS3TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL4223447 | 0.83 | NOS2 (0.47) | NOS2NOS1NOS3TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL4223453 | 0.83 | NOS2 (0.47) | NOS2NOS1NOS3TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL29401714 | 0.83 | NOS2 (0.47) | NOS2NOS1NOS3TSHRALDH1A1 | |
| Water SCHEMBL11206469 | 0.78 | TSHR (0.32) | NOS2NOS1NOS3TSHR | |
| Trifluoroacetic Acid SCHEMBL9659589 | 0.76 | NOS2 (0.42) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL7265290 | 0.76 | TSHR (0.36) | TSHRALDH1A1KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591758-A | ANGINA PECTORIS TREATMENT | LABORATOIRES HOECHST, SA (FR) | 1997-01-07 | — | — | US | disclosed |
| EP-0359399-B1 | Process for the enzymatic production of dipeptides | CARLBIOTECH LTD AS (DK) | 1994-03-16 | — | — | EP | disclosed |
| EP-0359399-A1 | Process for the enzymatic production of dipeptides | CARLBIOTECH LTD. A/S (DK) | 1990-03-21 | — | — | EP | disclosed |