Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894327 | 0.78 | EPHX2 (0.41) | HDAC8ALDH1A1FAAHMGLLELANE | |
| SCHEMBL8897567 | 0.78 | ALDH1A1 (0.56) | ALDH1A1FAAHMGLLMAPTLMNA | |
| SCHEMBL6050225 | 0.78 | ALDH1A1 (0.56) | ALDH1A1FAAHMGLLMAPTLMNA | |
| SCHEMBL10922619 | 0.78 | ALDH1A1 (0.56) | ALDH1A1FAAHMGLLMAPTLMNA | |
| SCHEMBL8895873 | 0.78 | ALDH1A1 (0.56) | ALDH1A1FAAHMGLLMAPTLMNA | |
| SCHEMBL9346157 | 0.78 | ALDH1A1 (0.56) | ALDH1A1FAAHMGLLMAPTLMNA | |
| SCHEMBL8895870 | 0.77 | SMN1; SMN2 (0.39) | HDAC8HSP90AA1ALDH1A1FAAHMGLL | |
| SCHEMBL8893675 | 0.76 | HSP90AA1 (0.44) | HDAC8HSP90AA1ALDH1A1FAAHMGLL | |
| SCHEMBL6966478 | 0.76 | ALDH1A1 (0.58) | ALDH1A1FAAHMGLLMAPTLMNA | |
| SCHEMBL18381162 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |