Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.77 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.58 |
| ▸ | PAM | P19021 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385058 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL8896965 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL7837014 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL3502039 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL5387189 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL7839076 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL7829125 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL938867 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL8893920 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 | |
| SCHEMBL8893739 | 1.00 | DGKA (0.77) | DGKADNM1TSHRPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |